| November 14, 2027 | LONGWOOD LANCERS | L 85-88 | 0-1 | B. Lowe 21 | B. Lowe 10 | K. Clay 5 |
| November 21, 2027 | SAN JOSE STATE SPARTANS Hall of Fame Classic | L 52-71 | 0-2 | A. Harvey 12 | B. Lowe 2 | K. Cheeks 6 |
| November 25, 2027 | OHIO STATE BUCKEYES | L 74-76 | 0-3 | A. Harvey 25 | B. Lowe 6 | W. Rolle 8 |
| November 29, 2027 | XAVIER MUSKETEERS | L 72-81 | 0-4 | A. Harvey 18 | B. Lowe 14 | K. Taylor 9 |
| December 1, 2027 | CLEVELAND STATE VIKINGS | W 86-76 | 1-4 | B. Lowe 16 | B. Lowe 6 | W. Rolle 5 |
| December 6, 2027 | PENNSYLVANIA QUAKERS | W 88-73 | 2-4 | B. Lowe 25 | T. Hobbs 7 | K. Taylor 10 |
| December 13, 2027 | SOUTH DAKOTA COYOTES | L 62-73 | 2-5 | B. Lowe 13 | K. Caldwell 4 | K. Clay 10 |
| December 17, 2027 | MISSISSIPPI REBELS | W 96-81 | 3-5 | K. Taylor 17 | B. Lowe 6 | K. Taylor 8 |
| December 20, 2027 | @ #25 Michigan State Spartans | W 74-71 | 4-5 | B. Lowe 25 | B. Lowe 4 | K. Caldwell 4 |
| December 28, 2027 | #4 WEST VIRGINIA MOUNTAINEERS* | W 92-86 | 5-5 | B. Lowe 23 | B. Lowe 7 | K. Clay 7 |
| January 2, 2028 | @ Arizona Wildcats (9-3, 0-1, 7-1 Home)* | - | | | | |
| January 4, 2028 | OKLAHOMA STATE COWBOYS (10-2, 1-1, 0-1 Away)* | - | | | | |
| January 6, 2028 | @ Texas Tech Red Raiders (9-3, 1-1, 8-0 Home)* | - | | | | |
| January 11, 2028 | @ Kansas State Wildcats (5-6, 0-2, 4-4 Home)* | - | | | | |
| January 13, 2028 | BRIGHAM YOUNG COUGARS (10-3, 1-1, 1-2 Away)* | - | | | | |
| January 18, 2028 | @ Iowa State Cyclones (10-3, 1-1, 7-0 Home)* | - | | | | |
| January 20, 2028 | KANSAS JAYHAWKS (14-0, 2-0, 3-0 Away)* | - | | | | |
| January 25, 2028 | ARIZONA WILDCATS (9-3, 0-1, 0-1 Away)* | - | | | | |
| January 27, 2028 | @ Baylor Bears (12-1, 2-0, 7-0 Home)* | - | | | | |
| January 30, 2028 | KANSAS STATE WILDCATS (5-6, 0-2, 1-1 Away)* | - | | | | |
| February 3, 2028 | @ Brigham Young Cougars (10-3, 1-1, 7-0 Home)* | - | | | | |
| February 8, 2028 | COLORADO BUFFALOES (6-6, 1-1, 1-3 Away)* | - | | | | |
| February 10, 2028 | @ Texas Christian Horned Frogs (9-4, 1-1, 6-1 Home)* | - | | | | |
| February 15, 2028 | @ Houston Cougars (9-3, 1-1, 7-1 Home)* | - | | | | |
| February 17, 2028 | UTAH UTES (4-7, 0-2, 0-3 Away)* | - | | | | |
| February 20, 2028 | @ Colorado Buffaloes (6-6, 1-1, 4-2 Home)* | - | | | | |
| February 24, 2028 | CENTRAL FLORIDA KNIGHTS (10-3, 1-1, 0-1 Away)* | - | | | | |
| February 27, 2028 | @ Kansas Jayhawks (14-0, 2-0, 7-0 Home)* | - | | | | |
| March 3, 2028 | CINCINNATI BEARCATS (12-1, 1-1, 1-1 Away)* | - | | | | |
