| November 15, 2027 | @ Arkansas State Red Wolves | W 78-67 | 1-0 | I. Farrell 19 | K. Wright 8 | A. Tillman 11 |
| November 18, 2027 | BELLARMINE KNIGHTS | L 67-83 | 1-1 | A. Tillman 16 | K. Wright 10 | A. Tillman 7 |
| November 21, 2027 | @ #12 North Carolina Tar Heels Charleston Classic | L 78-95 | 1-2 | A. Tillman 18 | K. Wright 7 | A. Tillman 4 |
| November 25, 2027 | @ Texas A&M Aggies | W 75-72 | 2-2 | A. Hammond 14 | K. Wright 7 | S. Stanley 11 |
| November 29, 2027 | @ Manhattan Jaspers | L 65-87 | 2-3 | I. Farrell 17 | K. Wright 5 | A. Tillman 6 |
| December 2, 2027 | @ UCLA Bruins | L 84-90 | 2-4 | A. Tillman 22 | K. Wright 9 | A. Tillman 11 |
| December 6, 2027 | HOWARD BISON | W 90-88 OT | 3-4 | A. Tillman 25 | K. Wright 7 | A. Tillman 10 |
| December 8, 2027 | @ #18 Texas Longhorns | L 69-83 | 3-5 | A. Tillman 20 | K. Wright 6 | A. Tillman 5 |
| December 13, 2027 | PENNSYLVANIA QUAKERS | L 73-90 | 3-6 | I. Farrell 16 | K. Wright 5 | S. Stanley 7 |
| December 21, 2027 | SACRAMENTO STATE HORNETS | L 69-75 | 3-7 | A. Tillman 16 | W. Bratton 6 | A. Tillman 12 |
| December 26, 2027 | LA SALLE EXPLORERS | W 69-65 | 4-7 | A. Hammond 16 | K. Wright 6 | I. Farrell 11 |
| January 3, 2028 | @ Hampton Pirates (3-8, 0-0, 2-2 Home)* | - | | | | |
| January 6, 2028 | CHARLESTON COUGARS (5-6, 0-0, 1-5 Away)* | - | | | | |
| January 10, 2028 | DELAWARE FIGHTIN' BLUE HENS (6-5, 0-0, 3-3 Away)* | - | | | | |
| January 13, 2028 | @ Campbell Fighting Camels (5-6, 0-0, 5-2 Home)* | - | | | | |
| January 17, 2028 | TOWSON TIGERS (5-6, 0-0, 2-6 Away)* | - | | | | |
| January 20, 2028 | @ Northeastern Huskies (6-7, 0-0, 2-2 Home)* | - | | | | |
| January 24, 2028 | @ Stony Brook Seawolves (5-6, 0-0, 2-2 Home)* | - | | | | |
| January 27, 2028 | HOFSTRA PRIDE (3-8, 0-0, 1-7 Away)* | - | | | | |
| January 31, 2028 | @ Charleston Cougars (5-6, 0-0, 4-0 Home)* | - | | | | |
| February 3, 2028 | HAMPTON PIRATES (3-8, 0-0, 1-6 Away)* | - | | | | |
| February 7, 2028 | @ William & Mary Tribe (4-7, 0-0, 2-3 Home)* | - | | | | |
| February 10, 2028 | ELON PHOENIX (2-10, 0-0, 1-7 Away)* | - | | | | |
| February 14, 2028 | @ NC-Wilmington Seahawks (6-6, 0-0, 4-1 Home)* | - | | | | |
| February 17, 2028 | NORTH CAROLINA A&T AGGIES (5-7, 0-0, 1-5 Away)* | - | | | | |
| February 21, 2028 | MONMOUTH HAWKS (5-6, 0-0, 2-2 Away)* | - | | | | |
| February 24, 2028 | @ Delaware Fightin' Blue Hens (6-5, 0-0, 3-2 Home)* | - | | | | |
| February 28, 2028 | CAMPBELL FIGHTING CAMELS (5-6, 0-0, 0-4 Away)* | - | | | | |
| March 3, 2028 | @ Towson Tigers (5-6, 0-0, 3-0 Home)* | - | | | | |
