| November 17, 2027 | @ Tennessee Tech Golden Eagles | W 80-77 | 1-0 | J. Chouest 17 | J. Stewart 4 | R. Badu 6 |
| November 26, 2027 | @ Mississippi Valley Delta Devils | W 82-74 | 2-0 | J. Chouest 26 | B. Towns 4 | V. Chavis 7 |
| November 29, 2027 | @ Rice Owls | L 83-89 OT | 2-1 | R. Badu 16 | B. Towns 5 | R. Badu 12 |
| December 1, 2027 | @ Fordham Rams | W 83-81 | 3-1 | J. Chouest 18 | B. Towns 8 | M. Villarreal 12 |
| December 6, 2027 | @ Mercer Bears | L 80-96 | 3-2 | J. Chouest 18 | B. Towns 4 | R. Badu 8 |
| December 10, 2027 | @ Coppin State Eagles | L 62-77 | 3-3 | J. Chouest 20 | B. Towns 5 | V. Chavis 6 |
| December 12, 2027 | @ Evansville Purple Aces | L 77-88 | 3-4 | B. Towns 23 | C. Edwards 5 | R. Badu 8 |
| December 16, 2027 | YALE BULLDOGS | L 69-92 | 3-5 | M. Griffith 14 | B. Towns 6 | R. Badu 9 |
| December 19, 2027 | OAKLAND GOLDEN GRIZZLIES | W 93-71 | 4-5 | C. Edwards 17 | B. Towns 7 | J. Chouest 7 |
| December 26, 2027 | @ Nicholls State Colonels* | W 106-99 | 5-5 | B. Towns 28 | B. Towns 9 | R. Badu 9 |
| December 29, 2027 | @ Texas A&M-CC Islanders* | W 81-67 | 6-5 | B. Towns 22 | B. Towns 8 | R. Badu 8 |
| January 2, 2028 | INCARNATE WORD CARDINALS* | L 58-70 | 6-6 | J. Stewart 13 | M. Bennett 4 | M. Villarreal 6 |
| January 5, 2028 | NORTHWESTERN STATE DEMONS* | W 90-75 | 7-6 | J. Chouest 14 | B. Towns 5 | R. Badu 8 |
| January 9, 2028 | SE LOUISIANA LIONS* | W 86-80 | 8-6 | V. Chavis 22 | B. Towns 3 | C. Edwards 6 |
| January 12, 2028 | @ Texas A&M-Comm. Lions* | L 76-77 | 8-7 | J. Chouest 15 | B. Towns 5 | J. Stewart 6 |
| January 16, 2028 | MCNEESE STATE COWBOYS* | L 67-81 | 8-8 | B. Towns 15 | B. Towns 5 | R. Badu 8 |
| January 19, 2028 | @ Texas-Rio Grande Vaqueros* | L 81-91 | 8-9 | J. Chouest 17 | B. Towns 7 | R. Badu 8 |
| January 23, 2028 | @ Stephen F. Austin Lumberjacks* | L 79-83 | 8-10 | J. Chouest 22 | B. Towns 5 | C. Edwards 6 |
| January 26, 2028 | @ McNeese State Cowboys* | L 71-87 | 8-11 | B. Towns 11 | B. Towns 4 | M. Villarreal 6 |
| January 30, 2028 | TEXAS-RIO GRANDE VAQUEROS* | W 92-71 | 9-11 | J. Chouest 23 | B. Towns 6 | R. Badu 6 |
| February 2, 2028 | STEPHEN F. AUSTIN LUMBERJACKS* | W 82-73 | 10-11 | B. Towns 17 | B. Towns 4 | R. Badu 7 |
| February 6, 2028 | TEXAS A&M-COMM. LIONS* | W 92-72 | 11-11 | B. Towns 14 | B. Towns 8 | R. Badu 7 |
| February 9, 2028 | HOUSTON CHRISTIAN HUSKIES* | L 74-86 | 11-12 | J. Chouest 16 | J. Chouest 5 | C. Edwards 6 |
| February 13, 2028 | @ Incarnate Word Cardinals* | L 53-74 | 11-13 | J. Chouest 11 | M. Griffith 4 | V. Chavis 7 |
| February 16, 2028 | @ Northwestern State Demons* | L 63-82 | 11-14 | C. Edwards 10 | B. Towns 3 | J. Chouest 6 |
| February 20, 2028 | NICHOLLS STATE COLONELS* | W 72-57 | 12-14 | J. Chouest 12 | M. Villarreal 3 | R. Badu 11 |
| February 23, 2028 | TEXAS A&M-CC ISLANDERS* | W 73-71 | 13-14 | B. Towns 16 | R. Badu 5 | R. Badu 9 |
| February 27, 2028 | @ Houston Christian Huskies* | L 68-96 | 13-15 | C. Edwards 14 | M. Bennett 4 | B. Towns 4 |
| March 2, 2028 | @ New Orleans Privateers* | L 72-93 | 13-16 | M. Griffith 12 | B. Towns 4 | R. Badu 6 |
| March 5, 2028 | @ Texas A&M-CC Islanders Southland Tournament | L 63-94 | 13-17 | B. Towns 15 | M. Villarreal 4 | R. Badu 9 |
