| November 15, 2027 | @ Arkansas Razorbacks | W 72-61 | 1-0 | E. Beck 24 | C. Hurd 5 | I. Ekpeyong 7 |
| November 18, 2027 | @ Texas Tech Red Raiders | L 69-87 | 1-1 | E. Beck 19 | C. McCarthy 6 | I. Ekpeyong 9 |
| November 22, 2027 | #13 BUTLER BULLDOGS | W 68-61 | 2-1 | C. McCarthy 19 | C. McCarthy 5 | C. Hurd 6 |
| November 29, 2027 | SOUTH CAROLINA GAMECOCKS | W 74-44 | 3-1 | C. McCarthy 13 | C. Hurd 6 | C. Hurd 10 |
| December 6, 2027 | UC-SANTA BARBARA GAUCHOS | W 90-69 | 4-1 | E. Beck 23 | E. Beck 5 | I. Ekpeyong 7 |
| December 9, 2027 | COLORADO STATE RAMS | W 60-54 | 5-1 | C. Hurd 15 | E. Beck 5 | D. Rozier 9 |
| December 13, 2027 | SAN DIEGO STATE AZTECS | W 77-76 OT | 6-1 | D. Rozier 22 | E. Beck 5 | D. Rozier 14 |
| December 20, 2027 | ARIZONA STATE SUN DEVILS | L 71-74 | 6-2 | C. Hurd 18 | C. Hurd 4 | I. Ekpeyong 8 |
| December 23, 2027 | FAIRFIELD STAGS Gulf Coast Showcase | W 59-56 | 7-2 | C. Hurd 16 | E. Beck 3 | I. Ekpeyong 9 |
| December 24, 2027 | SAINT LOUIS BILLIKENS Gulf Coast Showcase | W 73-60 | 8-2 | I. Ekpeyong 15 | C. McCarthy 4 | C. Hurd 7 |
| December 25, 2027 | TEXAS CHRISTIAN HORNED FROGS Gulf Coast Showcase | L 72-80 | 8-3 | E. Beck 23 | C. McCarthy 8 | C. Hurd 11 |
| December 26, 2027 | RUTGERS SCARLET KNIGHTS* | W 71-68 | 9-3 | E. Beck 21 | E. Beck 6 | C. Hurd 6 |
| December 28, 2027 | @ Indiana Hoosiers* | L 59-89 | 9-4 | C. Hurd 15 | R. Renault 4 | D. Rozier 8 |
| January 2, 2028 | @ Oregon Ducks (6-6, 1-1, 5-4 Home)* | - | | | | |
| January 4, 2028 | WASHINGTON HUSKIES (7-4, 1-1, 0-1 Away)* | - | | | | |
| January 9, 2028 | @ Southern California Trojans (8-3, 2-0, 8-3 Home)* | - | | | | |
| January 11, 2028 | MINNESOTA GOLDEN GOPHERS (9-4, 2-0, 0-2 Away)* | - | | | | |
| January 16, 2028 | @ Iowa Hawkeyes (4-7, 0-2, 4-3 Home)* | - | | | | |
| January 18, 2028 | NEBRASKA CORNHUSKERS (5-6, 0-2, 0-3 Away)* | - | | | | |
| January 23, 2028 | @ UCLA Bruins (10-3, 1-1, 6-2 Home)* | - | | | | |
| January 25, 2028 | @ Illinois Fighting Illini (8-3, 2-0, 6-1 Home)* | - | | | | |
| January 30, 2028 | WISCONSIN BADGERS (10-3, 1-1, 1-2 Away)* | - | | | | |
| February 1, 2028 | @ Michigan Wolverines (12-1, 1-1, 8-0 Home)* | - | | | | |
| February 6, 2028 | PURDUE BOILERMAKERS (9-3, 2-0, 2-0 Away)* | - | | | | |
| February 8, 2028 | MARYLAND TERRAPINS (9-3, 1-1, 2-2 Away)* | - | | | | |
| February 13, 2028 | @ Penn State Nittany Lions (4-7, 1-1, 4-3 Home)* | - | | | | |
| February 15, 2028 | @ Ohio State Buckeyes (7-5, 0-2, 5-1 Home)* | - | | | | |
| February 20, 2028 | NORTHWESTERN WILDCATS (5-6, 0-2, 0-2 Away)* | - | | | | |
| February 22, 2028 | IOWA HAWKEYES (4-7, 0-2, 0-3 Away)* | - | | | | |
| February 27, 2028 | INDIANA HOOSIERS (7-4, 2-0, 1-2 Away)* | - | | | | |
| March 1, 2028 | @ Nebraska Cornhuskers (5-6, 0-2, 5-2 Home)* | - | | | | |
