| November 16, 2027 | JACKSONVILLE DOLPHINS | W 74-61 | 1-0 | P. Althoff 18 | J. Wrenn 8 | R. Perry 9 |
| November 18, 2027 | #22 XAVIER MUSKETEERS | W 90-83 | 2-0 | A. Johnson 30 | J. Wrenn 9 | P. Althoff 13 |
| November 21, 2027 | INDIANA STATE SYCAMORES Charleston Classic | W 89-76 | 3-0 | A. Johnson 33 | J. Wrenn 3 | P. Althoff 7 |
| November 22, 2027 | TEXAS TECH RED RAIDERS Charleston Classic | W 84-69 | 4-0 | P. Althoff 18 | A. Johnson 5 | E. Clark 12 |
| November 23, 2027 | @ #12 North Carolina Tar Heels Charleston Classic | L 70-87 | 4-1 | A. Johnson 15 | E. Clark 3 | E. Clark 9 |
| November 26, 2027 | WEST GEORGIA WOLFPACK | W 86-67 | 5-1 | P. Althoff 29 | A. Johnson 6 | E. Clark 10 |
| November 28, 2027 | @ St. Bonaventure Bonnies | L 69-80 | 5-2 | P. Althoff 20 | E. Clark 3 | E. Clark 9 |
| December 2, 2027 | WAGNER SEAHAWKS | W 76-58 | 6-2 | P. Althoff 18 | J. Wrenn 4 | E. Clark 15 |
| December 6, 2027 | @ Butler Bulldogs | L 67-77 | 6-3 | B. Hill 16 | R. Perry 7 | R. Perry 6 |
| December 14, 2027 | LIBERTY FLAMES | W 94-74 | 7-3 | A. Johnson 22 | J. Wrenn 8 | E. Clark 10 |
| December 20, 2027 | ILLINOIS STATE REDBIRDS | L 82-85 | 7-4 | J. Thompson 15 | R. Perry 4 | R. Perry 13 |
| December 26, 2027 | PENN STATE NITTANY LIONS* | W 91-71 | 8-4 | J. Wrenn 18 | J. Wrenn 6 | E. Clark 10 |
| December 28, 2027 | #3 MICHIGAN WOLVERINES* | W 85-73 | 9-4 | A. Johnson 28 | J. Wrenn 5 | R. Perry 8 |
| January 2, 2028 | @ Wisconsin Badgers (10-3, 1-1, 6-1 Home)* | - | | | | |
| January 4, 2028 | PURDUE BOILERMAKERS (9-3, 2-0, 2-0 Away)* | - | | | | |
| January 9, 2028 | @ Maryland Terrapins (9-3, 1-1, 6-0 Home)* | - | | | | |
| January 11, 2028 | @ Michigan State Spartans (9-4, 1-1, 6-1 Home)* | - | | | | |
| January 16, 2028 | @ Illinois Fighting Illini (8-3, 2-0, 6-1 Home)* | - | | | | |
| January 18, 2028 | WASHINGTON HUSKIES (7-4, 1-1, 0-1 Away)* | - | | | | |
| January 23, 2028 | SOUTHERN CALIFORNIA TROJANS (8-3, 2-0, 0-0 Away)* | - | | | | |
| January 25, 2028 | @ Oregon Ducks (6-6, 1-1, 5-4 Home)* | - | | | | |
| January 30, 2028 | @ Rutgers Scarlet Knights (5-7, 0-2, 4-3 Home)* | - | | | | |
| February 1, 2028 | UCLA BRUINS (10-3, 1-1, 2-0 Away)* | - | | | | |
| February 6, 2028 | NORTHWESTERN WILDCATS (5-6, 0-2, 0-2 Away)* | - | | | | |
| February 8, 2028 | INDIANA HOOSIERS (7-4, 2-0, 1-2 Away)* | - | | | | |
| February 13, 2028 | OHIO STATE BUCKEYES (7-5, 0-2, 1-3 Away)* | - | | | | |
| February 15, 2028 | @ Nebraska Cornhuskers (5-6, 0-2, 5-2 Home)* | - | | | | |
| February 20, 2028 | @ Iowa Hawkeyes (4-7, 0-2, 4-3 Home)* | - | | | | |
| February 22, 2028 | @ Purdue Boilermakers (9-3, 2-0, 6-2 Home)* | - | | | | |
| February 27, 2028 | OREGON DUCKS (6-6, 1-1, 0-1 Away)* | - | | | | |
| March 1, 2028 | @ UCLA Bruins (10-3, 1-1, 6-2 Home)* | - | | | | |
