| November 15, 2027 | SIENA SAINTS | W 82-65 | 1-0 | R. McLean 21 | T. Ohanlon 5 | J. DeVone 10 |
| November 18, 2027 | BOISE STATE BRONCOS | W 93-88 | 2-0 | T. Ohanlon 28 | B. Woodley 5 | T. Ohanlon 6 |
| November 22, 2027 | COLGATE RAIDERS | L 73-84 | 2-1 | T. Ohanlon 17 | B. Woodley 7 | J. DeVone 8 |
| November 25, 2027 | UTAH TECH TRAILBLAZERS | L 67-73 | 2-2 | B. Walker 14 | B. Woodley 4 | R. McLean 11 |
| November 29, 2027 | EASTERN KENTUCKY COLONELS | W 66-57 | 3-2 | B. Walker 13 | R. McLean 5 | T. Ohanlon 10 |
| December 6, 2027 | JACKSON STATE TIGERS | W 64-59 | 4-2 | T. Ohanlon 14 | B. Woodley 4 | B. Walker 10 |
| December 13, 2027 | UTAH VALLEY WOLVERINES | W 74-65 | 5-2 | J. DeVone 19 | B. Woodley 4 | T. Ohanlon 8 |
| December 20, 2027 | FORDHAM RAMS | L 78-83 | 5-3 | T. Ohanlon 26 | B. Woodley 6 | J. DeVone 8 |
| December 23, 2027 | SAINT LOUIS BILLIKENS Gulf Coast Showcase | L 58-67 | 5-4 | T. Ohanlon 18 | B. Woodley 4 | R. McLean 14 |
| December 26, 2027 | NOTRE DAME FIGHTING IRISH* | L 67-70 | 5-5 | B. Woodley 14 | B. Woodley 5 | R. McLean 7 |
| December 28, 2027 | #12 DUKE BLUE DEVILS* | L 69-93 | 5-6 | T. Ohanlon 22 | B. Woodley 4 | B. Walker 8 |
| January 2, 2028 | @ Virginia Cavaliers (12-1, 2-0, 5-0 Home)* | - | | | | |
| January 4, 2028 | @ Florida State Seminoles (8-5, 0-2, 6-2 Home)* | - | | | | |
| January 9, 2028 | CALIFORNIA GOLDEN BEARS (8-3, 2-0, 2-0 Away)* | - | | | | |
| January 11, 2028 | @ Virginia Tech Hokies (7-4, 2-0, 6-3 Home)* | - | | | | |
| January 16, 2028 | @ Pittsburgh Panthers (10-4, 0-2, 7-1 Home)* | - | | | | |
| January 18, 2028 | NORTH CAROLINA TAR HEELS (11-2, 2-0, 0-0 Away)* | - | | | | |
| January 23, 2028 | @ Louisville Cardinals (11-2, 2-0, 7-1 Home)* | - | | | | |
| January 25, 2028 | CLEMSON TIGERS (8-4, 1-1, 0-1 Away)* | - | | | | |
| January 30, 2028 | MIAMI (FL) HURRICANES (6-5, 0-2, 0-4 Away)* | - | | | | |
| February 1, 2028 | @ Georgia Tech Yellow Jackets (10-3, 1-1, 6-0 Home)* | - | | | | |
| February 6, 2028 | @ Wake Forest Demon Deacons (7-4, 1-1, 7-2 Home)* | - | | | | |
| February 8, 2028 | @ Stanford Cardinal (10-3, 1-1, 7-2 Home)* | - | | | | |
| February 13, 2028 | SYRACUSE ORANGE (3-8, 0-2, 0-0 Away)* | - | | | | |
| February 15, 2028 | BOSTON COLLEGE EAGLES (6-6, 0-2, 0-4 Away)* | - | | | | |
| February 20, 2028 | SOUTHERN METHODIST MUSTANGS (5-7, 0-2, 0-2 Away)* | - | | | | |
| February 22, 2028 | @ Notre Dame Fighting Irish (7-5, 2-0, 4-3 Home)* | - | | | | |
| February 27, 2028 | @ Duke Blue Devils (9-4, 2-0, 6-1 Home)* | - | | | | |
| March 1, 2028 | FLORIDA STATE SEMINOLES (8-5, 0-2, 0-2 Away)* | - | | | | |
