| November 15, 2027 | TEXAS-SAN ANTONIO ROADRUNNERS | W 75-47 | 1-0 | E. Kresse 18 | P. Bell 4 | E. Kresse 18 |
| November 18, 2027 | SIENA SAINTS | W 71-63 | 2-0 | M. Trilli 17 | L. Dawson 7 | E. Kresse 7 |
| November 22, 2027 | LA SALLE EXPLORERS | W 75-49 | 3-0 | P. Dye 16 | P. Bell 5 | E. Kresse 7 |
| November 25, 2027 | VERMONT CATAMOUNTS Myrtle Beach Invitational | W 66-55 | 4-0 | B. Spears 17 | P. Bell 5 | E. Kresse 11 |
| November 26, 2027 | PROVIDENCE FRIARS Myrtle Beach Invitational | L 76-84 | 4-1 | B. Spears 14 | P. Bell 5 | D. Patton 5 |
| November 29, 2027 | TEXAS A&M-CC ISLANDERS | L 81-84 OT | 4-2 | D. Patton 25 | P. Bell 7 | E. Kresse 14 |
| December 2, 2027 | SOUTH ALABAMA JAGUARS | W 68-54 | 5-2 | L. Dawson 17 | R. Wilson 6 | D. Patton 11 |
| December 6, 2027 | DELAWARE FIGHTIN' BLUE HENS | L 56-60 | 5-3 | D. Patton 14 | R. Wilson 4 | E. Kresse 12 |
| December 13, 2027 | MOREHEAD STATE EAGLES | L 51-64 | 5-4 | D. Patton 10 | L. Dawson 5 | D. Patton 10 |
| December 20, 2027 | @ Texas Christian Horned Frogs | L 72-79 | 5-5 | P. Bell 17 | P. Bell 5 | E. Kresse 10 |
| December 26, 2027 | @ NC-State Wolfpack* | W 70-67 | 6-5 | P. Bell 17 | E. Kresse 4 | D. Patton 7 |
| December 28, 2027 | @ Syracuse Orange* | W 82-75 | 7-5 | M. Trilli 18 | L. Dawson 6 | E. Kresse 15 |
| January 2, 2028 | PITTSBURGH PANTHERS (10-4, 0-2, 0-2 Away)* | - | | | | |
| January 4, 2028 | @ Louisville Cardinals (11-2, 2-0, 7-1 Home)* | - | | | | |
| January 9, 2028 | @ Clemson Tigers (8-4, 1-1, 8-3 Home)* | - | | | | |
| January 11, 2028 | GEORGIA TECH YELLOW JACKETS (10-3, 1-1, 1-3 Away)* | - | | | | |
| January 16, 2028 | @ California Golden Bears (8-3, 2-0, 6-2 Home)* | - | | | | |
| January 18, 2028 | @ Duke Blue Devils (9-4, 2-0, 6-1 Home)* | - | | | | |
| January 23, 2028 | @ Boston College Eagles (6-6, 0-2, 5-1 Home)* | - | | | | |
| January 25, 2028 | @ Southern Methodist Mustangs (5-7, 0-2, 4-4 Home)* | - | | | | |
| January 30, 2028 | FLORIDA STATE SEMINOLES (8-5, 0-2, 0-2 Away)* | - | | | | |
| February 1, 2028 | VIRGINIA CAVALIERS (12-1, 2-0, 4-1 Away)* | - | | | | |
| February 6, 2028 | VIRGINIA TECH HOKIES (7-4, 2-0, 1-1 Away)* | - | | | | |
| February 8, 2028 | @ Miami (FL) Hurricanes (6-5, 0-2, 6-0 Home)* | - | | | | |
| February 13, 2028 | NORTH CAROLINA TAR HEELS (11-2, 2-0, 0-0 Away)* | - | | | | |
| February 15, 2028 | STANFORD CARDINAL (10-3, 1-1, 0-1 Away)* | - | | | | |
| February 20, 2028 | @ Wake Forest Demon Deacons (7-4, 1-1, 7-2 Home)* | - | | | | |
| February 22, 2028 | NC-STATE WOLFPACK (5-6, 0-2, 0-0 Away)* | - | | | | |
| February 27, 2028 | SOUTHERN METHODIST MUSTANGS (5-7, 0-2, 0-2 Away)* | - | | | | |
| March 1, 2028 | DUKE BLUE DEVILS (9-4, 2-0, 1-2 Away)* | - | | | | |
