| November 15, 2027 | TOWSON TIGERS | L 71-81 | 0-1 | D. Strohm 16 | W. Tann 7 | D. Townes 11 |
| November 18, 2027 | SAINT FRANCIS (PA) RED FLASH | W 84-64 | 1-1 | E. Wilcox 19 | W. Tann 5 | D. Strohm 10 |
| November 21, 2027 | DUQUESNE DUKES Hall of Fame Classic | L 85-90 OT | 1-2 | E. Wilcox 21 | W. Tann 7 | E. Wilcox 9 |
| November 25, 2027 | @ San Diego Toreros | L 82-92 | 1-3 | D. Townes 18 | W. Tann 4 | R. Chenowith 6 |
| November 29, 2027 | MONTANA STATE BOBCATS | W 77-52 | 2-3 | E. Wilcox 18 | W. Tann 6 | E. Wilcox 11 |
| December 2, 2027 | HOFSTRA PRIDE | L 68-75 | 2-4 | E. Wilcox 23 | W. Tann 4 | E. Wilcox 11 |
| December 6, 2027 | MEMPHIS TIGERS | W 82-72 | 3-4 | D. Townes 18 | D. Strohm 5 | D. Townes 8 |
| December 13, 2027 | @ Oregon State Beavers | W 78-60 | 4-4 | D. Townes 21 | W. Tann 9 | E. Wilcox 11 |
| December 20, 2027 | NORTHWESTERN WILDCATS | W 79-76 OT | 5-4 | E. Wilcox 22 | W. Tann 8 | D. Townes 8 |
| December 26, 2027 | DEPAUL BLUE DEMONS* | W 96-84 | 6-4 | R. Chenowith 27 | D. Strohm 4 | R. Chenowith 5 |
| December 28, 2027 | @ Connecticut Huskies* | W 71-56 | 7-4 | W. Tann 19 | G. Romano 4 | R. Chenowith 8 |
| December 30, 2027 | @ Xavier Musketeers* | L 57-76 | 7-5 | D. Townes 15 | W. Tann 4 | D. Strohm 6 |
| January 2, 2028 | GEORGETOWN HOYAS (9-2, 0-2, 2-1 Away)* | - | | | | |
| January 4, 2028 | @ Providence Friars (9-4, 1-1, 5-3 Home)* | - | | | | |
| January 6, 2028 | CREIGHTON BLUE JAYS (10-4, 1-2, 0-2 Away)* | - | | | | |
| January 13, 2028 | SETON HALL PIRATES (10-3, 1-1, 1-1 Away)* | - | | | | |
| January 18, 2028 | @ Butler Bulldogs (9-4, 2-0, 4-1 Home)* | - | | | | |
| January 20, 2028 | @ Marquette Golden Eagles (13-1, 2-0, 7-1 Home)* | - | | | | |
| January 27, 2028 | VILLANOVA WILDCATS (10-3, 2-1, 4-1 Away)* | - | | | | |
| February 1, 2028 | PROVIDENCE FRIARS (9-4, 1-1, 1-1 Away)* | - | | | | |
| February 3, 2028 | @ Seton Hall Pirates (10-3, 1-1, 6-2 Home)* | - | | | | |
| February 8, 2028 | MARQUETTE GOLDEN EAGLES (13-1, 2-0, 2-0 Away)* | - | | | | |
| February 10, 2028 | BUTLER BULLDOGS (9-4, 2-0, 2-3 Away)* | - | | | | |
| February 15, 2028 | @ Creighton Blue Jays (10-4, 1-2, 8-1 Home)* | - | | | | |
| February 17, 2028 | @ Villanova Wildcats (10-3, 2-1, 5-1 Home)* | - | | | | |
| February 22, 2028 | @ Georgetown Hoyas (9-2, 0-2, 7-1 Home)* | - | | | | |
| February 24, 2028 | @ DePaul Blue Demons (7-4, 0-2, 6-1 Home)* | - | | | | |
| March 1, 2028 | XAVIER MUSKETEERS (6-7, 1-2, 2-2 Away)* | - | | | | |
| March 3, 2028 | CONNECTICUT HUSKIES (4-8, 1-1, 0-1 Away)* | - | | | | |
