| November 15, 2026 | ROBERT MORRIS COLONIALS | W 91-71 | 1-0 | T. Melson 25 | T. Clemmons 7 | T. Clemmons 8 |
| November 19, 2026 | PENNSYLVANIA QUAKERS | W 81-65 | 2-0 | T. Clemmons 22 | T. Melson 3 | K. Higgins 11 |
| November 22, 2026 | SO. CAROLINA UPSTATE SPARTANS | W 73-55 | 3-0 | T. Melson 21 | T. Clemmons 10 | T. Clemmons 7 |
| November 24, 2026 | @ #7 Iowa State Cyclones | L 87-89 | 3-1 | T. Melson 18 | T. Clemmons 5 | K. Higgins 17 |
| December 3, 2026 | HARVARD CRIMSON | L 82-86 | 3-2 | M. Coffee 23 | T. Clemmons 6 | M. Coffee 9 |
| December 6, 2026 | LONG BEACH STATE SHARKS | W 86-58 | 4-2 | K. Higgins 22 | T. Clemmons 5 | K. Adams 10 |
| December 8, 2026 | LIPSCOMB BISONS | W 74-68 | 5-2 | T. Melson 18 | T. Clemmons 4 | K. Higgins 9 |
| December 16, 2026 | RADFORD HIGHLANDERS | W 93-61 | 6-2 | M. Coffee 20 | T. Clemmons 9 | K. Higgins 12 |
| December 19, 2026 | KANSAS STATE WILDCATS | W 100-85 | 7-2 | T. Melson 25 | T. Clemmons 6 | K. Adams 8 |
| December 26, 2026 | @ Virginia Cavaliers* | L 83-85 | 7-3 | K. Higgins 20 | T. Clemmons 4 | K. Higgins 15 |
| December 28, 2026 | @ Virginia Tech Hokies* | W 73-58 | 8-3 | T. Clemmons 17 | T. Clemmons 7 | K. Higgins 12 |
| January 2, 2027 | #19 CLEMSON TIGERS* | W 95-81 | 9-3 | T. Melson 29 | T. Melson 7 | K. Adams 8 |
| January 4, 2027 | PITTSBURGH PANTHERS* | L 80-89 | 9-4 | T. Clemmons 15 | T. Clemmons 5 | K. Higgins 6 |
| January 9, 2027 | #8 DUKE BLUE DEVILS* | L 70-93 | 9-5 | M. Coffee 21 | T. Clemmons 4 | T. Clemmons 5 |
| January 11, 2027 | #1 NORTH CAROLINA TAR HEELS* | L 90-96 | 9-6 | T. Melson 22 | T. Clemmons 8 | M. Coffee 6 |
| January 16, 2027 | @ Wake Forest Demon Deacons* | W 93-75 | 10-6 | K. Higgins 27 | T. Clemmons 8 | K. Higgins 11 |
| January 18, 2027 | LOUISVILLE CARDINALS* | W 103-92 | 11-6 | T. Clemmons 35 | T. Clemmons 6 | K. Adams 10 |
| January 23, 2027 | GEORGIA TECH YELLOW JACKETS* | W 90-67 | 12-6 | T. Melson 26 | T. Melson 6 | K. Higgins 14 |
| January 25, 2027 | MIAMI (FL) HURRICANES* | W 83-70 | 13-6 | T. Melson 28 | T. Clemmons 5 | K. Higgins 12 |
| January 30, 2027 | @ Stanford Cardinal* | W 88-66 | 14-6 | T. Melson 24 | T. Clemmons 5 | K. Higgins 10 |
| February 1, 2027 | @ Boston College Eagles* | W 95-82 | 15-6 | T. Melson 23 | T. Clemmons 7 | K. Higgins 9 |
| February 6, 2027 | NC-STATE WOLFPACK* | W 76-64 | 16-6 | M. Coffee 18 | T. Clemmons 6 | K. Higgins 9 |
| February 8, 2027 | @ Florida State Seminoles* | L 85-97 | 16-7 | T. Melson 23 | T. Clemmons 4 | K. Higgins 7 |
| February 13, 2027 | @ Notre Dame Fighting Irish* | L 65-78 | 16-8 | K. Higgins 20 | T. Clemmons 4 | K. Higgins 7 |
| February 15, 2027 | #23 CALIFORNIA GOLDEN BEARS* | L 69-80 | 16-9 | T. Melson 18 | T. Clemmons 5 | K. Adams 6 |
| February 20, 2027 | SYRACUSE ORANGE* | W 88-58 | 17-9 | K. Higgins 23 | T. Clemmons 4 | K. Higgins 9 |
| February 22, 2027 | @ #21 California Golden Bears* | W 79-72 | 18-9 | T. Melson 24 | T. Clemmons 10 | M. Coffee 7 |
| February 27, 2027 | @ Miami (FL) Hurricanes* | W 76-59 | 19-9 | T. Melson 17 | T. Clemmons 3 | K. Higgins 7 |
| March 1, 2027 | @ Pittsburgh Panthers* | W 90-88 OT | 20-9 | T. Melson 22 | T. Clemmons 6 | K. Higgins 8 |
| March 9, 2027 | WAKE FOREST DEMON DEACONS ACC Tournament | L 100-103 | 20-10 | T. Clemmons 31 | T. Melson 4 | K. Higgins 12 |
| March 17, 2027 | @ California Golden Bears NCAA Tournament | L 68-79 | 20-11 | T. Melson 16 | T. Clemmons 6 | K. Higgins 8 |
