| November 16, 2027 | TEXAS STATE BOBCATS | W 70-65 | 1-0 | T. Mitchell 16 | T. Murphy 7 | T. Murphy 5 |
| November 18, 2027 | #18 MICHIGAN STATE SPARTANS | W 87-69 | 2-0 | D. Battle 25 | T. Murphy 5 | T. Gordon 7 |
| November 21, 2027 | WESTERN MICHIGAN BRONCOS Charleston Classic | W 64-51 | 3-0 | D. Battle 18 | T. Murphy 4 | T. Gordon 10 |
| November 22, 2027 | @ Minnesota Golden Gophers Charleston Classic | L 69-84 | 3-1 | M. Granger 15 | T. Murphy 3 | T. Gordon 8 |
| November 30, 2027 | PORTLAND STATE VIKINGS | W 75-55 | 4-1 | B. Blanks 19 | T. Murphy 5 | T. Gordon 11 |
| December 3, 2027 | RIDER BRONCS | W 71-62 | 5-1 | D. Battle 14 | D. Battle 3 | T. Gordon 9 |
| December 7, 2027 | SACRAMENTO STATE HORNETS | W 83-75 | 6-1 | T. Gordon 14 | T. Murphy 5 | T. Mitchell 7 |
| December 14, 2027 | NC-CENTRAL EAGLES | W 66-55 | 7-1 | T. Gordon 12 | D. Battle 3 | T. Gordon 10 |
| December 21, 2027 | PRAIRIE VIEW PANTHERS | W 73-59 | 8-1 | B. Blanks 16 | T. Murphy 4 | T. Murphy 9 |
| December 24, 2027 | @ Mississippi State Bulldogs | L 62-72 | 8-2 | T. Gordon 16 | T. Murphy 5 | T. Gordon 10 |
| December 26, 2027 | @ Brigham Young Cougars* | L 68-72 | 8-3 | T. Gordon 17 | K. Donovan 4 | D. Battle 6 |
| December 30, 2027 | #8 CINCINNATI BEARCATS* | W 90-84 | 9-3 | S. Price 18 | T. Murphy 4 | T. Mitchell 8 |
| January 4, 2028 | @ #22 Baylor Bears* | W 68-67 | 10-3 | D. Battle 20 | T. Murphy 3 | D. Battle 10 |
| January 6, 2028 | ARIZONA STATE SUN DEVILS* | W 81-68 | 11-3 | T. Gordon 19 | T. Murphy 4 | M. Granger 9 |
| January 11, 2028 | @ Colorado Buffaloes* | L 77-82 | 11-4 | T. Gordon 20 | T. Murphy 5 | T. Gordon 9 |
| January 13, 2028 | #12 OKLAHOMA STATE COWBOYS* | W 107-99 OT | 12-4 | T. Gordon 18 | D. Battle 6 | T. Gordon 9 |
| January 18, 2028 | CENTRAL FLORIDA KNIGHTS* | W 82-73 | 13-4 | T. Mitchell 14 | T. Murphy 3 | T. Gordon 11 |
| January 20, 2028 | @ #23 Houston Cougars* | W 83-74 | 14-4 | T. Mitchell 14 | D. Battle 5 | T. Mitchell 9 |
| January 25, 2028 | @ Texas Christian Horned Frogs* | L 78-87 | 14-5 | T. Gordon 16 | D. Battle 4 | T. Mitchell 6 |
| January 30, 2028 | #3 WEST VIRGINIA MOUNTAINEERS* | L 64-75 | 14-6 | D. Battle 13 | D. Battle 4 | S. Price 11 |
| February 1, 2028 | @ #6 Arizona Wildcats* | L 61-91 | 14-7 | T. Gordon 19 | D. Battle 3 | T. Mitchell 7 |
| February 3, 2028 | HOUSTON COUGARS* | W 67-64 | 15-7 | T. Gordon 21 | I. Babul 4 | T. Gordon 13 |
| February 8, 2028 | TEXAS CHRISTIAN HORNED FROGS* | W 89-73 | 16-7 | T. Mitchell 17 | T. Murphy 7 | T. Mitchell 6 |
| February 10, 2028 | @ Kansas State Wildcats* | W 81-72 | 17-7 | T. Gordon 16 | M. Granger 4 | T. Gordon 8 |
| February 15, 2028 | @ #2 West Virginia Mountaineers* | L 59-75 | 17-8 | T. Gordon 12 | T. Murphy 3 | I. Babul 7 |
| February 17, 2028 | IOWA STATE CYCLONES* | W 79-71 | 18-8 | T. Gordon 16 | T. Murphy 4 | T. Gordon 7 |
| February 22, 2028 | BAYLOR BEARS* | W 75-71 | 19-8 | B. Blanks 15 | T. Murphy 4 | T. Gordon 7 |
| February 24, 2028 | @ #5 Kansas Jayhawks* | L 73-76 | 19-9 | T. Gordon 14 | K. Donovan 5 | I. Babul 7 |
| March 1, 2028 | #22 BRIGHAM YOUNG COUGARS* | W 69-60 | 20-9 | B. Blanks 13 | D. Battle 5 | T. Gordon 11 |
| March 3, 2028 | @ Utah Utes* | W 79-63 | 21-9 | K. Donovan 17 | I. Babul 4 | T. Mitchell 9 |
| March 10, 2028 | #22 BRIGHAM YOUNG COUGARS Big 12 Tournament | L 59-68 | 21-10 | T. Gordon 11 | T. Murphy 5 | M. Granger 7 |
